Production began in London earlier this month on Best Interests, a new BBC One drama from prolific writer Jack Thorne.

The 4 x 60 stars Sharon Horgan and Michael Sheen and comes from Chapter One Pictures in association with Endeavor Content. Michael Keillor directs; Jenn Frayn produces.

The drama centres on a family driven apart by having to make choices no parent would ever want to make. Horgan and Sheen play married couple Nicci and Andrew, who have two daughters: Katie and Marnie.

Marnie has a life-threatening condition. The doctors believe it is in her best interests to be allowed to die, but her loving family disagree. And so begins a fight that will take them through every stage of a legal process, as they struggle to contemplate this huge decision…

Thorne said: “Best Interests cases are both compelling and revealing. Our country has a very troubled relationship with disability and these cases put a spotlight on that. But our drama is first and foremost a love story and it needs incredible actors to bring it to life.

“Sharon Horgan and Michael Sheen lead a company of ridiculous talents that pull you into the most interesting of places. I’m so grateful to be working with them, Chapter One, Michael Keillor and a very brilliant crew.”

Horgan added: “Best Interests broke me when I first read the script and then again after talking with Jack about it. Covid seems to have shone a closer light on the desperate inequalities that exist for our disabled community so this felt very timely. It”s a big subject but it”s in Jack Thorne and Michael Keillor”s safe hands. I”m thrilled to be working on this story with a super talented cast, the wonderful Michael Sheen and Noma Dumezweni, and my gorgeous daughters; Alison Oliver and Niamh Moriarty.”

Best Interests is executive produced by Sophie Gardiner, Toby Bentley with Thorne for One Shoe Films, and Lucy Richer for BBC One.